Dr. Karen Herbst recommends the following supplements:

• Beta Glucan
• Selenium
• Bioflavonoids such as horse chestnut seed extract and Quercetin
  
• Enzymes such as Serrapeptase and Wobenzyme

You can read about her supplement protocol here www.lipomadoc.org/lipedema.html

Be sure to consult with your health care provider before embarking on a supplement program.